xCT Transporter Assay (SLC7A11)

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xCT Transporter Assay

Relevance – Amino acid transport, neurotransmission,  anti-oxidative defense Single or Multi-Transporter Model – Single
Transporter Type – Uptake Cell Model – MDCK-II
Assay Type – Intracellular accumulation Exactly Matched Control Cells – Yes
Species – Human Probe Substrate – Glutamic acid
Subcellular Localization in Assay Model – Basolateral Inhibition Positive Control – Sulfasalazine

Clinical & Regulatory Relevance

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Applications & Therapeutic Areas

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